Information Station

This Guy Will Change The World

This is a snippet of Dr Ravi Majeti’s latest research;

Ravi Majeti, MD, PhD, rips away cancer’s disguise so the body can eat it.

“Don’t eat me!” That’s what CD47, a protein on the surface of baby blood cells, broadcasts to the immune system as these cells make their maiden voyage from bone marrow to spleen. Without this chemical signal, many normal cells like these could be mistaken for invaders and gobbled up by macrophages, the body’s roving cellular garbage disposals.

Researchers at Stanford’s Institute for Stem Cell Biology and Regenerative Medicine found that leukemia cells also express a lot of CD47. So Ravi Majeti and his team, with the leadership of the Institute’s director Irv Weissman, MD, set out to discover if CD47 was the chemical disguise leukemia cells used to escape detection by the immune system.

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